Federalwide Assurances and IRB Registration

Federalwide Assurances

Penn operates under Federalwide Assurances (FWAs) in accordance Subpart A 46.103a which requires any institution engaged in non-exempt human subjects research conducted or supported by HHS to submit a written assurance of compliance to OHRP. Renewal is required every 5 years. Any updates made to the FWAs begins a new 5-year effective period. 

University of Pennsylvania: FWA00004028, Expires: 4/5/2026

Penn Medicine Princeton Health**: FWA00009852, Expires: 2/09/2027

**Utilize for research conducted at Princeton Health and relying on an external IRB such as NCI CIRB.

IORG Number

The Institution or Organization (IORG) number is a unique number assigned by OHRP to an institution or organization the first time an institution or organization registers an IRB. The IORG number for the University of Pennsylvania is IORG0000029.

IRB Registration Information

All of the Penn IRBs listed under the FWAs are registered electronically in accordance with 45 CFR 46,§ 501-505. Renewal is required every 3 years. Any updates made to the IRB registration begins a new 3-year registration period. Each IRB registered under an FWA has a unique registration number which are listed below. In certain circumstances, a funding agency or sponsor may request the institutional or IRB registration numbers/identifiers for Penn IRBs. 

IRBs 1-7 reviewing FDA-regulated research are required to provide FDA-specific information to the federal OHRP. These IRBs are fully compliant with the FDA registration requirements. To view the Penn IRB registrations, go to the OHRP website. Select the IRB Organizations (IORG) radio button for document type. Enter the IORG Number above. 

**Click here to read FDA's notice regarding registration of IRBs reviewing FDA-Regulated Research.

Expires: 10/16/2023

Registration Identifier IRB Name IRB Type
IRB00000038 IRB #1 OHRP/FDA
IRB00000039 IRB #2 OHRP/FDA
IRB00000040 IRB #3 OHRP/FDA
IRB00000041 IRB #4 OHRP/FDA
IRB00000042 IRB #5 OHRP/FDA
IRB00000043 IRB #6 OHRP/FDA
IRB00000044 IRB #7 OHRP/FDA
IRB00002997 IRB #8 OHRP only